Yazar "Coban, Neslihan" için listeleme
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Association of polymorphisms in the sex hormone genes with the presence and severity of coronary artery disease
Coban, Neslihan; Ozuynuk, Aybike Sena; Erkan, Aycan Fahri; Kaya, Aysem; Ekici, Berkay; Guclu-Geyik, Filiz; Erginel-Unaltuna, Nihan (Aves, 2022)Objective: Coronary artery disease (CAD) is an important public health problem worldwide. Therefore, it is important to identify the molecular mechanisms and the candidate gene polymorphisms involved in the development of ... -
Examining the effects of the CLU and APOE polymorphisms' combination on coronary artery disease complexed with type 2 diabetes mellitus
Ozuynuk, Aybike Sena; Erkan, Aycan Fahri; Dogan, Nazli; Ekici, Berkay; Erginel-Unaltuna, Nihan; Kurmus, Ozge; Coban, Neslihan (Elsevier Science Inc, 2022)Aims: Coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) are important and increasing public health problems. This study aimed to identify the impact of APOE and CLU gene polymorphisms on the prevalence of ... -
Examining the expression levels of ferroptosis-related genes in angiographically determined coronary artery disease patients
Ozuynuk, Aybike Sena; Erkan, Aycan Fahri; Coban, Neslihan; Unaltuna, Nihan (Springer, 2022)Background Cardiovascular diseases are the leading cause of death worldwide, with several conditions being affected by oxidative stress. Ferroptosis, recently identified programmed cell death mechanism, is relies on oxidative ... -
Investigation of miR-26a-5p and miR-19a-3p expression levels in angiographically confirmed coronary artery disease
Coban, Neslihan; Erkan, Aycan F. F.; Ozuynuk-Ertugrul, Aybike Sena; Ekici, Berkay (Taylor & Francis Ltd, 2023)BackgroundMicroRNAs have been found to have an essential role in cardiovascular diseases. In previous experiments, the changed expressions of miR-26a-5p and miR-19a-3p were confirmed in patients with severe coronary ... -
Levels of miR-130b-5p in peripheral blood are associated with severity of coronary artery disease
Coban, Neslihan; Ozuynuk, Aybike Sena; Erkan, Aycan Fahri; Guclu-Geyik, Filiz; Ekici, Berkay (Springer, 2021)Background Although patients with coronary artery disease (CAD) have a high mortality rate, the pathogenesis of CAD is still poorly understood. During the past decade, microRNAs (miRNAs) have emerged as new, potential ... -
Makrofaj migrasyon inhibitör faktör (MIF) geni -173 G>C polimorfizminin koroner arter hastalığı ve tip 2 diyabet ile ilişkisi
Coban, Neslihan; Erkan, Aycan Fahri; Ekici, Berkay; Kasit, Maide; Unaltuna, Nihan Erginel; Vurgun, Eren (Turkish Soc Cardiology, 2019)Objective: Recent studies indicate that macrophage migration inhibitory factor (MIF) is a potent proinflammatory cytokine which mediates the inflammatory process during atherosclerosis. The purpose of the study was to ... -
Val109Asp polymorphism in Intelectin 1 gene is associated with coronary artery disease severity in women
Guclu-Geyik, Filiz; Erkan, Aycan Fahri; Ozuynuk, Aybike Sena; Ekici, Berkay; Coban, Neslihan (Aves, 2022)Objective: Intelectin-1 is an anti-inflammatory adipokine encoded by the Intelectin 1 (ITLN1) gene. Genetic variations in the ITLN1 gene affect the risk of coronary artery disease (CAD) and related CAD risk factors. In ...