Yazar "Demirtaş Korkmaz, Funda" için listeleme
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Alzheimer's drug Memantine inhibits metastasis and p-Erk protein expression on 4T1 breast cancer cells
Albayrak, Gülşah; Demirtaş Korkmaz, Funda (Comenius Univ, 2020)OBJECTIVES: Drug repurposing studies enable shorter routes to the clinic by skipping the steps like in vitro in vivo screening, chemical optimization and toxicological studies. In our study, we investigated the potent ... -
Memantine shifts cancer cell metabolism via ampk1/2 mediated energetic switch in a549 lung cancer cells
Memantine is used to prevent glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease. As glutamine is one of the major source of anabolism in fast growing cancer cells, we aimed to interfere with ...