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Flavopiridol induces apoptosis via mitochondrial pathway in B16F10 murine melanoma cells and a subcutaneous melanoma tumor model
Gökçe, Özlem; Turaçlı, İrem Doğan; Önen, Hacer ilke; Erdem, Özlem; Kaya, Elif Ergüven; Ekmekçi, Abdullah (Croatian Dermatovenerological Society, 2016)Flavopiridol is a cyclin-dependent kinase (CDK) inhibitor that promotes cell cycle arrest. We aimed to examine the anti-proliferative effects of the flavopiridol and oxaliplatin combination on p16INK4A deficient melanoma ...