Browsing by Author "Çandar, Tuba"
Now showing items 1-20 of 35
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An assesment of unexpectedly high HbA1c level in a case with type 1 diabetes
Çandar, Tuba; Özdemir, Sedat; Ergür, Ayça Törel; Demirtaş, Selda (Nobel Ilac, 2016)The HbA1c test provides information about blood glucose levels of previous months depending on the erythrocyte lifetime when monitoring diabetic patients. However, various factors such as HbF and other hemoglobin variants ... -
The association between ischemia modified albumin and placental histopathology in uncomplicated term deliveries
Kiseli, Mine; Gürsoy, Aslı Yarcı; Akıncıoğlu, Egemen; Çağlar, Gamze Sinem; Çandar, Tuba; Demirtaş, Selda (2015)Ischemia modified albumin (IMA) is a marker of ischemia elevated in different clinical conditions and its use for hypoxia in perinatology is of current interest. We aimed to investigate the association between maternal ... -
Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case-control study
Hayran, Yildiz; Allı, Nuran; Uysal, Pınar İncel; Çandar, Tuba (Elsevier Science Inc, 2020)Background: Cytochrome P450 2J2 is mostly expressed in extrahepatic tissues; it metabolizes arachidonic acid to epoxyeicosatrienoic acids, with various cardio protective and anti-inflammatory effects. CYP2J2 polymorphism ... -
Behçet's: a disease or a syndrome? answer from an expression profiling study
Oğuz, Ali Kemal; Yılmaz, Seda Taşır; Oygür, Çağdaş Şahap; Çandar, Tuba; Sayın, Irmak; Kılıçoğlu, Sibel Serin; Ergün, İhsan (Public Library Science, 2016)Behcet's disease (BD) is a chronic, relapsing, multisystemic inflammatory disorder with unanswered questions regarding its etiology/pathogenesis and classification. Distinct manifestation based subsets, pronounced geographical ... -
CRP at early follicular phase of menstrual cycle can cause misinterpretation for cardiovascular risk assessment
Gürsoy, Aslı Yarcı; Çağlar, Gamze Sinem; Kiseli, Mine; Pabuçcu, Emre; Çandar, Tuba; Demirtaş, Selda (2015)Objective: C-reactive protein (CRP) is a well-known marker of infl ammation and infection in clinical practice. This study is designed to evaluate CRP levels in diff erent phases of menstrual cycle, which might end up ... -
Do follicular fluid advanced glycation end products levels affect the ovarian response in unexplained infertility?
Seven, Banu; Taşçı, Yasemin; Gülerman, Cavidan; Çandar, Tuba; Kokanalı, Kuntay; Yüksel, Yasemin; Bardakçı, Yesim; Engin-Üstün, Yaprak (2021)Objective: To compare the advanced glycation end products (AGEs) levels in follicular fluid according to the different ovarian responses of women who underwent controlled ovarian stimulation due to unexplained infertility ... -
Do MCF7 cells cope with metformin treatment under energetic stress in low glucose conditions?
Turaçlı, İrem Doğan; Umudum, Haldun; Pampal, Arzu; Çandar, Tuba; Kavasoğlu, Lara; Sarı, Yaren (2018-02-03)There is a growing body of evidence about metformin being effective in cancer therapy. Despite controversies about the ways of its effectiveness, several ongoing clinical trials are evaluating the drug when used as an ... -
The effect of folate on ischemia/reperfusion injury in a rat adnexal torsion model
Çandar, Tuba; Uzunlar, Özlem; Kiseli, Mine; Özcan, Sarp (2021)Purpose The ischemia/reperfusion (I/R) injury of ovaries in adnexal torsion may have inadvertent consequences. Many agents have been studied in terms of their ability to prevent reperfusion damage to ovaries in suspected ... -
The effect of serum electrolyte disturbances and uric acid level on the mortality of patients with acute exacerbation of chronic obstructive pulmonary disease
Objectives: The aim of the study was to determine the prevalence of electrolyte and uric acid disturbances and their effects on mortality in patients with acute exacerbations of chronic obstructive pulmonary disease ... -
The effects of water immersion and epidural analgesia on cellular immune response, neuroendocrine, and oxidative markers
Background/aim: Water immersion and epidural analgesia are the most preferred pain relief methods during the labor process. Adverse effects related to these methods, impact on the labor, and perception of pain is well ... -
Elevated serum calprotectin as an inflammatory marker in obstructive sleep apnea
Kum, Nurcan Yurtsever; Kum, Rauf Oguzhan; Çandar, Tuba; Baklacı, Deniz; Güler, İsmail; Kuzucu, İhsan; Özcan, Kürşat Murat (2020)OBJECTIVE To investigate the serum calprotectin (SCal) levels and neutrophil/lymphocyte ratio (NLR) values in patients with obstructive sleep apnea (OSA). METHODS Sixty-seven OSA patients and 46 healthy volunteers without ... -
Galectin-3, IL-1A, IL-6, and EGF levels in corneal epithelium of patients with recurrent corneal erosion syndrome
Purpose: To determine the galectin-3 (Gal3), interleukin-1 (IL-1), interleukin-6 (IL-6), and epidermal growth factor (EGF) levels in corneal epithelium of patients with recurrent corneal erosion (RCE) syndrome and compare ... -
Hearing tresholds and serum apelin levels in patients with vertebrobasilar ınsufciency
Ezerarslan, Hande; Çandar, Tuba; Özdemir, Sedat; Kaan Ataç, Gökçe; Kocatürk, Sinan; Demirtaş, Selda (2014)Amaç: Vertebrobaziler yetmezlik (VBY) vertebral arter ve dallarında oluşan hemodinamik değişiklikler sonu- cunda akım hacminin azalması ile oluşan klinik tablo- dur. Bu çalışmanın amacı baş dönmesi şikayeti ile baş- vuran ... -
The impact of nuchal cord on umbilical cord blood gas analysis and ischaemia-modified albumin levels in elective C-section
Yarcı Gürsoy, Aslı; Özgü, Burçin; Tasçı, Yasemin; Çandar, Tuba; Erkaya, Salim; Çağlar, Gamze Sinem (2018)This study was designed to evaluate umbilical cord ischaemia-modified albumin (IMA) levels and the cord blood gas parameters of foetuses with or without nuchal cords, at the time of elective C-section. The cross-sectional ... -
Increased anti-EBV VCA IgG antibody levels are associated with need for surgery in patients developing upper respiratory tract complications
Arslan, Hande; Çandar, Tuba; Vural, Özge (Elsevier Ireland Ltd, 2018)Introduction: The immune reaction developing against Ebstein-Barr virus (EBV) infection may be one of the major determinants of severe adenoid hypertrophy (AH) and chronic otitis media with effusion (COME) needing surgery. ... -
Is ischemia modified albumin a good marker in acute exacerbation of chronic obstructive pulmonary disease?
Objectives: Our aim is to compare the Ischemia modified albumin (IMA) in patients with acute exacerbationof Chronic Obstructive Pulmonary Disease (COPD) with a high oxidative and inflammatory biologic markerlike C-reactive ... -
Is there an association between liver type fatty acid binding protein and severity of preeclampsia?
Uzunlar, Özlem; Üstün, Yaprak Engin; Özyer, Şebnem; Danışman, Nuri; Çandar, Tuba; Keskin, Senem; Mollamahmutoğlu, Leyla (2015)Objective The aim of this study was to estimate the level of liver fatty acid binding protein (LFABP) in women with preeclampsia. Method A case–control study was conducted in 90 pregnant women who were divided into the ... -
The levels of matrix metalloproteinase-9 and neutrophil gelatinase-associated lipocalin in different stages of endometriosis
Durmuş, Arzu Bostancı; Cengiz, Sevim Dinçer; Yılmaz, Hakan; Çandar, Tuba; Gürsoy, Aslı Yarcı; Çağlar, Gamze Sinem (2019)This study was designed to explore matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) levels and MMP-9/NGAL ratio in women with and without endometriosis diagnosed surgically and/or ... -
Maternal serum advanced glycation end products level as an early marker for predicting preterm labor/PPROM: a prospective preliminary study
Kansu Çelik, Hatice; Taşçı, Yasemin; Kısa Karakaya, Burcu; Çınar, Mehmet; Çandar, Tuba; Çağlar, Gamze Sinem (2018)Objective: To evaluate the value of maternal serum advanced glycation end products (AGEs) level at 11–13 weeks’ gestation for the prediction of preterm labor and or preterm premature rupture of membranes (PPROM). Materials ...
