Browsing by Author "Huang, Zhen"

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Thrombin-receptor antagonist vorapaxar in acute coronary syndromes

Tricoci, Pierluigi; Huang, Zhen; Held, Claes; Moliterno, David; Armstrong, Paul; Werf, Frans Van de; White, Harvey; Erkan, Aycan (2012)

BACKGROUND Vorapaxar is a new oral protease-activated–receptor 1 (PAR-1) antagonist that inhibits thrombin-induced platelet activation. METHODS In this multinational, double-blind, randomized trial, we compared vorapaxar ...
Vorapaxar, a platelet thrombin-receptor antagonist, in medically managed patients with non-ST-segment elevation acute coronary syndrome: results from the TRACER trial

Held, Claes; Tricoci, Pierluigi; Huang, Zhen; Van de Werf, Frans; White, Harvey D.; Armstrong, Paul W.; Mahaffey, Kenneth W. (Sage Publications Ltd, 2014)

Background: This study characterized a medically managed population in a non-ST-segment elevation acute coronary syndrome (NSTEACS) cohort and evaluated prognosis and outcomes of vorapaxar vs. placebo. Methods: In the ...