Predictive Values of Serum Uric Acid, Mean Platelet Volume and Plateletcrit on Benign Paroxysmal Positional Vertigo

Abstract

Aim: There are conflicting study results on correlation of serum uric acid (SUA) with benign paroxysmal positional vertigo (BPPV). In this study, it was aimed to evaluate predictive values of SUA, mean platelet volume (MPV) and plateletcrit (PTC) on BPPV. Materials and Methods: After the approval of the ethics committee, the files of all patients with BPPV who were admitted to the Emergency Department of Ufuk University between 01.01.2015 and 01.01.2016 were examined retrospectively. White blood cell, MPV, FTC and SUA levels of patients were evaluated. Results: There was no statistically significant difference between the groups in terms of gender distribution (p0.05). The mean age of the control group (31.25 +/- 11.46 years) was lower than the vertigo group (44.71 +/- 19.38 years), but this difference was not statistically significant (p>0.05). The difference between two groups in terms of MPV, PTC and SUA parameters was statistically significant (p<0.05). The sensitivity was found to be 92.1% and the specificity was 47.8%. For a FTC value of 0.224%, the sensitivity was 23.7% and the specificity was 87%. For SUA, area under curve was 71.6% indicating that SUA had a predictive value for peripheral vertigo (p<0.01). The sensitivity of SUA was 55.3% and the specificity was 21.7% for a SUA value of 4.1. The sensitivity of SUA was 15.8 and the specificity was 87% for a SUA value of 6.55. Conclusion: Analysis results were in accordance with volume ure in which SUA is suspected in idiopathic BPPV. In addition, PTC was also correlated with BPPV.