dc.contributor.author | Ozdemir, Elif Didem | |
dc.contributor.author | Caglar, Gamze Sinem | |
dc.contributor.author | Akgul, Ebru | |
dc.contributor.author | Cengiz, Sevim Dincer | |
dc.contributor.author | Tombak, Gamze | |
dc.date.accessioned | 2022-03-10T19:29:22Z | |
dc.date.available | 2022-03-10T19:29:22Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0378-7346 | |
dc.identifier.issn | 1423-002X | |
dc.identifier.uri | https://doi.org/10.1159/000362550 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14065/2729 | |
dc.description.abstract | Aims: To evaluate the association between serum prolactin, high-sensitivity C-reactive protein (hs-CRP) levels and cardiovascular disease risk in postmenopausal women regarding the Framingham Risk Score (FRS). Methods: Fifty-eight menopausal women were enrolled into the cross-sectional study. All participants had 24-hour ambulatory blood pressure monitoring, echocardiography, electrocardiography, and carotid intima-media thickness measurement. Blood samples were obtained for prolactin, hs-CRP, lipid profile, fasting glucose, and insulin. Results: Among the participants, 67.24% had a FRS < 10%, and 32.75% had a FRS >= 10%. Levels of prolactin and hs-CRP did not differ between the FRS groups. In the FRS < 10% group, significantly higher levels of prolactin were found. Cases with hypertension have significantly higher levels of hs-CRP. Prolactin and hs-CRP were found to be associated with hypertension in the FRS < 10% and >= 10% groups, respectively. Conclusions: Hypertensive postmenopausal women with low risk for cardiovascular diseases have increased levels of prolactin, suggesting a possible role in the pathogenesis of hypertension. The correlation of hs-CRP with systolic blood pressure can be interpreted as a potential effect of hypertensive: heart disease reflecting a state of high-risk milieu with elevated inflammatory markers. (C) 2014 S. Karger AG, Basel | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Karger | en_US |
dc.relation.ispartof | Gynecologic and Obstetric Investigation | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Prolactin | en_US |
dc.subject | High-sensitivity C-reactive protein | en_US |
dc.subject | Menopause | en_US |
dc.subject | Cardiovascular disease | en_US |
dc.subject | Coronary-Heart-Disease | en_US |
dc.subject | Metabolic Syndrome | en_US |
dc.subject | Women | en_US |
dc.subject | Hypertension | en_US |
dc.subject | Markers | en_US |
dc.title | The Association between Prolactin, High-Sensitivity C-Reactive Protein and Framingham Risk Score in Menopause | en_US |
dc.type | article | en_US |
dc.department | Ufuk Üniversitesi | en_US |
dc.identifier.doi | 10.1159/000362550 | |
dc.identifier.volume | 78 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 119 | en_US |
dc.identifier.endpage | 123 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 55486057500 | |
dc.authorscopusid | 55879368100 | |
dc.authorscopusid | 6701335317 | |
dc.authorscopusid | 6701512448 | |
dc.authorscopusid | 56174061600 | |
dc.identifier.wos | WOS:000340812500007 | en_US |
dc.identifier.scopus | 2-s2.0-84908356068 | en_US |
dc.identifier.pmid | 24861467 | en_US |