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dc.contributor.authorErkan, Aycan Fahri
dc.contributor.authorTanındı, Aslı
dc.contributor.authorKocaman, Sinan Altan
dc.contributor.authorUğurlu, Murat
dc.contributor.authorTöre, Hasan Fehmi
dc.date.accessioned2022-03-10T19:29:37Z
dc.date.available2022-03-10T19:29:37Z
dc.date.issued2016
dc.identifier.citationErkan, A. F., Tanindi, A., Kocaman, S. A., Ugurlu, M., & Tore, H. F. (2016). Epicardial Adipose Tissue Thickness Is an Independent Predictor of Critical and Complex Coronary Artery Disease by Gensini and Syntax Scores. Texas Heart Institute Journal, 43(1), 29–37. https://doi.org/10.14503/thij-14-4850
dc.identifier.issn1526-6702
dc.identifier.urihttps://doi.org/10.14503/THIJ-14-4850
dc.identifier.urihttps://hdl.handle.net/20.500.14065/2799
dc.description.abstractEpicardial adipose tissue thickness is associated with the severity and extent of atherosclerotic coronary artery disease. We prospectively investigated whether epicardial adipose tissue thickness is related to coronary artery disease extent and complexity as denoted by Gensini and Syntax scores, and whether the thickness predicts critical disease. After performing coronary angiography in 183 patients who had angina or acute myocardial infarction, we divided them into 3 groups: normal coronary arteries, noncritical disease (>= 1 coronary lesion with < 70% stenosis), and critical disease (>= 1 coronary lesion with >= 70% stenosis). We used transthoracic echocardiography to measure epicardial adipose tissue thickness, then calculated Gensini and Syntax scores by reviewing the angiograms. Mean thicknesses were 4.3 +/- 0.9, 5.2 +/- 1.5, and 7.5 +/- 1.9 mm in patients with normal coronary arteries, noncritical disease, and critical disease, respectively (P < 0.001). At progressive thicknesses (< 5, 5-7, and > 7 mm), mean Gensini scores were 4.1 +/- 5.5, 19.8 +/- 15.6, and 64.9 +/- 32.4, and mean Syntax scores were 4.7 +/- 5.9, 16.6 +/- 8.5, and 31.7 +/- 8.7, respectively (both P < 0.001). Thickness had strong and positive correlations with both scores (Gensini, r = 0.82, P < 0.001; and Syntax, r = 0.825, P < 0.001). The cutoff thickness value to predict critical disease was 5.75 mm (area under the curve, 0.875; 95% confidence interval, 0.825-0.926; P < 0.001). Epicardial adipose tissue thickness is independently related to coronary artery disease extent and complexity as denoted by Gensini and Syntax scores, and it predicts critical coronary artery disease.en_US
dc.language.isoengen_US
dc.publisherTexas Heart Instituteen_US
dc.relation.ispartofTexas Heart Institute Journalen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdipose tissue/pathology/physiology/ultrasonographyen_US
dc.subjectAtherosclerosis/physiopathologyen_US
dc.subjectCoronary artery disease/diagnosisen_US
dc.subjectEchocardiographyen_US
dc.subjectForecastingen_US
dc.subjectPatient selectionen_US
dc.subjectPredictive value of testsen_US
dc.subjectProspective studiesen_US
dc.subjectSensitivity and specificityen_US
dc.subjectFat thicknessen_US
dc.subjectMetabolic syndromeen_US
dc.subjectClinical-applicationsen_US
dc.subjectPeriadventitial faten_US
dc.subjectDiabetes-mellitusen_US
dc.subjectAtherosclerosisen_US
dc.subjectSeverityen_US
dc.subjectVolumeen_US
dc.subjectMetaanalysisen_US
dc.subjectAssociationen_US
dc.titleEpicardial adipose tissue thickness is an independent predictor of critical and complex coronary artery disease by gensini and SYNTAX scoresen_US
dc.typearticleen_US
dc.authoridErkan, Aycan Fahri / 0000-0002-9469-7149
dc.authoridTöre, Hasan Fehmi / 0000-0002-6657-1880
dc.departmentTıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyolojien_US
dc.institutionauthorErkan, Aycan Fahri
dc.institutionauthorTanındı, Aslı
dc.institutionauthorUğurlu, Murat
dc.institutionauthorTöre, Hasan Fehmi
dc.identifier.doi10.14503/THIJ-14-4850
dc.identifier.volume43en_US
dc.identifier.issue1en_US
dc.identifier.startpage29en_US
dc.identifier.endpage37en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorwosidErkan, Aycan Fahri / AAN-5880-2021
dc.authorscopusid6602309202
dc.authorscopusid16176601000
dc.authorscopusid19933921100
dc.authorscopusid56549721000
dc.authorscopusid6602380465
dc.identifier.wosqualityQ4
dc.identifier.wosWOS:000374244200008en_US
dc.identifier.scopus2-s2.0-84956909221en_US
dc.identifier.pmid27047282en_US


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