dc.contributor.author | Bilgihan, Kamil | |
dc.contributor.author | Yesilirmak, Nilufer | |
dc.contributor.author | Altay, Yesim | |
dc.contributor.author | Tefon, Atike B. | |
dc.contributor.author | Ozdemir, Huseyin B. | |
dc.contributor.author | Ozdogan, Sibel | |
dc.contributor.author | Gurelik, Gokhan | |
dc.date.accessioned | 2022-03-10T19:37:21Z | |
dc.date.available | 2022-03-10T19:37:21Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1542-2321 | |
dc.identifier.issn | 1542-233X | |
dc.identifier.uri | https://doi.org/10.1097/ICL.0000000000000585 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14065/3279 | |
dc.description | 51st TOA National Congress -- OCT 24-29, 2017 -- Antalya, TURKEY | en_US |
dc.description.abstract | Purpose: To evaluate long-term corneal morphological changes after photorefractive keratectomy (PRK) using in vivo confocal microscopy (IVCM) and specular microscopy. Methods: This comparative case-control study included 16 eyes of 8 patients who underwent PRK for mild to moderate myopia 20 years ago and 30 eyes of 15 sex- and age-matched healthy controls. Corneal epithelial cells, sub-basal nerves, keratocytes (anterior, midstromal, and posterior), and endothelial cells were evaluated in both groups 10 and 20 years after surgery. Long-term visual outcomes were also recorded. Results: In vivo confocal microscopy examination revealed similar epithelial morphology, sub-basal nerve fiber morphology/density, mid/posterior stromal keratocyte density, and endothelial cell density between PRK patients and controls at their 10th and 20th year follow-up. Anterior stromal keratocyte density was lower at 10th year; however, it reached to control group value at 20th year follow-up. Extracellular matrix reflectivity was slightly higher, and there was a trace subepithelial corneal haze in PRK group (milder in 20th year than 10th year) compared with controls. At the 20th year, uncorrected distance visual acuity was 20/20 or more in 6 eyes (37.5%), 20/40 or more in 16 eyes (100%), and all eyes had corrected distance visual acuity of 20/20 or better (spherical equivalent -0.31 +/- 0.37 D). Conclusions: Photorefractive keratectomy in low to moderate myopia seems to be safe and effective method in the long term with preserving corneal morphology (including anterior stromal keratocyte and sub-basal nerve fiber density) and refractive outcomes as shown in this study. In appropriate patients, this method can be considered confidently. | en_US |
dc.description.sponsorship | TOA | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins | en_US |
dc.relation.ispartof | Eye & Contact Lens-Science and Clinical Practice | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | In vivo confocal microscopy | en_US |
dc.subject | Specular microscopy | en_US |
dc.subject | Long-term follow-up | en_US |
dc.subject | Surgery | en_US |
dc.subject | Density | en_US |
dc.title | Evaluation of Long-Term Corneal Morphology After Photorefractive Keratectomy by In Vivo Confocal Microscopy and Specular Microscopy; 20-Year Follow-Up | en_US |
dc.type | conferenceObject | en_US |
dc.authorid | Özdemir, Hüseyin Baran / 0000-0002-5585-253X | |
dc.authorid | Yesilirmak, Nilufer/0000-0002-8632-2873 | |
dc.department | Ufuk Üniversitesi | en_US |
dc.identifier.doi | 10.1097/ICL.0000000000000585 | |
dc.identifier.volume | 45 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 360 | en_US |
dc.identifier.endpage | 364 | en_US |
dc.relation.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
dc.authorwosid | Özdemir, Hüseyin Baran/L-5252-2018 | |
dc.authorwosid | Yesilirmak, Nilufer/AAD-7299-2020 | |
dc.authorwosid | bilgihan, kamil/AAB-6864-2022 | |
dc.authorscopusid | 7003694065 | |
dc.authorscopusid | 55602579600 | |
dc.authorscopusid | 6507604332 | |
dc.authorscopusid | 57203534817 | |
dc.authorscopusid | 56992492300 | |
dc.authorscopusid | 36786498300 | |
dc.authorscopusid | 57140738200 | |
dc.identifier.wos | WOS:000511858800003 | en_US |
dc.identifier.scopus | 2-s2.0-85074308847 | en_US |
dc.identifier.pmid | 31170117 | en_US |