Latencies to first interictal epileptiform discharges in different seizure types during video-EEG monitoring

View/ Open
Access
info:eu-repo/semantics/openAccessDate
2019Author
Koç, GürayMorkavuk, Gülin
Akkaya, Efdal
Karadaş, Ömer
Leventoğlu, Alev
Ünay, Bülent
Gökçil, Zeki
Metadata
Show full item recordCitation
Koc, Guray, et al. “Latencies to First Interictal Epileptiform Discharges in Different Seizure Types during Video-EEG Monitoring.” Seizure, 69, 235-240. pubmed.ncbi.nlm.nih.gov/31121547/, 10.1016/j.seizure.2019.05.013. Accessed 28 Oct. 2022.Abstract
Purpose: Interictal epileptiform discharges (IEDs) have high diagnostic value concerning patients with epilepsy
and the instances of obtaining IEDs increase with longer recording times. However, the merit of a single, extended
electroencephalography (EEG) recording in detecting IEDs has not been substantiated. We aimed to
determine the optimal duration of an EEG required to diagnose epilepsy in different seizure types.
Methods: Overall, 84 patients—29 with generalised onset epilepsy and 55 with focal onset epilepsy—were
evaluated. Long-term video electroencephalographic monitoring (VEM) was analysed to find the first definite
IED besides assessing the first seizure and latency.
Results: The median latency of the first IED (12 min, ranging from 1 to 440 min vs. 55 min, ranging from 2 to
7500 min; p= 0.014) and the median duration of a VEM recording (2 d, ranging from 1 to 10 d vs. 3 d, ranging
from 1 to 10 d; p= 0.012) were found significantly lower in the generalised epilepsy group compared with that
in the focal epilepsy group.
Conclusions: Generalised onset epilepsy showed a significantly shorter latency to IED and VEM duration compared
with focal onset epilepsy. In our data set, all the patients with generalised onset epilepsy had interictal IED
within 10 h, but the patients with focal onset epilepsy required monitoring for three days to obtain IED.