The assessment of the relationship between the vascularity of FIGO Type 4-7 leiomyomas and abnormal uterine bleeding

Abstract

The current study aimed to analyse and compare the vascularity of FIGO Type 4–7 leiomyoma speci mens obtained from women with or without abnormal uterine bleeding (AUB). The records of 31 women who underwent myomectomy for FIGO Type 4–7 leiomyomas in a university hospital setting were analysed. Group I (n ¼ 16) was composed of women that were symptomatic for AUB and group II (n ¼ 15) consisted of asymptomatic cases. The myomectomy material(s) of each case were processed with CD34 staining and evaluated by Image JVR software (Image J 1.52a, Wayne Rasband National Institutes of Health, Bethesda, MD). There was no statistically significant difference between the rates of vascular areas in the specimens of the two groups (p>.05). Although areas with large vessels were higher in group I compared to group II, the difference did not reach statistical significance (p>.05). AUB caused by FIGO Type 4–7 leiomyomas seems to be related to factors other than vascular density.