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dc.contributor.authorAkgül, Ebru
dc.contributor.authorKütük, Utku
dc.contributor.authorErtek, Sibel
dc.contributor.authorCesur, Mustafa
dc.contributor.authorÇehreli, Şengül
dc.contributor.authorTöre, Hasan Fehmi
dc.contributor.authorErdoğan, Gündüz
dc.date.accessioned2022-03-10T19:25:08Z
dc.date.available2022-03-10T19:25:08Z
dc.date.issued2011
dc.identifier.citationAkgul, E., Kutuk, U., Ertek, S., Cesur, M., Cehreli, S., Tore, H. F., & Erdogan, G. (2011). Cardiac Autonomic Function and Global Left Ventricular Performance in Autoimmune Eauthyroid Chronic Thyroiditis: Is Treatment Necessary at the Euthyroid Stage? Echocardiography, 28(1), 15–21. https://doi.org/10.1111/j.1540-8175.2010.01240.x
dc.identifier.issn0742-2822
dc.identifier.urihttps://doi.org/10.1111/j.1540-8175.2010.01240.x
dc.identifier.urihttps://hdl.handle.net/20.500.14065/2604
dc.description.abstractObjective: Autoimmune chronic thyroiditis (ACT) is characterized by lymphocyte infiltration in the thyroid gland and the presence of antithyroid antibodies in serum. Medical treatment does not affect antibody levels and treatment decision is not definite yet for the euthyroid patients. We aimed to evaluate cardiac autonomic function and global left ventricular performance in autoimmune euthyroid chronic thyroiditis and determine the need for medical treatment. Method: We studied 30 ACT patients and 25 healthy control subjects. Cardiac autonomic function is evaluated by heart rate recovery (HRR). Global left ventricular performance is evaluated by two-dimensional echocardiography and pulsed-wave tissue Doppler echocardiography. Results: There was no difference between patients and controls with respect to clinical and biochemical parameters except hemoglobin (13.67 +/- 1.25 g/dL, 14.51 +/- 1.35 g/dL, p:0.047) and low density lipoprotein (120.71 +/- 24.91 mg/dL, 100.55 +/- 14.73 mg/dL, p: 0.003). Tei index was significantly higher in ACT group (0.521 +/- 0.074, 0.434 +/- 0.034, P < 0.0001). E'/A' was found to be significantly lower (1.234 +/- 0.42, 1.750 +/- 0.291, P < 0.0001) and E/E' was found to be higher than the controls (8.482 +/- 0.449, 6.039 +/- 0.209, P < 0.0001). HRR was significantly lower than the controls (20 +/- 4 BPM, 30 +/- 8 BPM, P < 0.0001). Conclusion: Although left ventricular performance is found to be normal by conventional echocardiographic methods, it is found to be impaired when Tei index and tissue Doppler parameters are used. Cardiac autonomic function is also impaired in ACT patients. As a result of these cardiac changes, medical treatment may be considered earlier, even at the euthyroid stage. (Echocardiography 2011;28:15-21).en_US
dc.language.isoengen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofEchocardiography - A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAutoimmune chronic thyroiditisen_US
dc.subjectCardiac autonomic functionen_US
dc.subjectHeart rate recovery (HRR)en_US
dc.subjectMyocardial performance indexen_US
dc.subjectPulsed-wave tissue Doppleren_US
dc.titleCardiac autonomic function and global left ventricular performance in autoimmune eauthyroid chronic thyroiditis: is treatment necessary at the euthyroid stage?en_US
dc.typearticleen_US
dc.authoridCesur, Mustafa / 0000-0002-1029-2604
dc.authoridErtek, Sibel / 0000-0002-9283-0292
dc.authoridTöre, Hasan Fehmi / 0000-0002-6657-1880
dc.departmentTıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyolojien_US
dc.departmentTıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Endokrinoloji ve Metabolizma
dc.institutionauthorAkgül, Ebru
dc.institutionauthorKütük, Utku
dc.institutionauthorErtek, Sibel
dc.institutionauthorCesur, Mustafa
dc.institutionauthorÇehreli, Şengül
dc.institutionauthorTöre, Hasan Fehmi
dc.institutionauthorErdoğan, Gündüz
dc.identifier.doi10.1111/j.1540-8175.2010.01240.x
dc.identifier.volume28en_US
dc.identifier.issue1en_US
dc.identifier.startpage15en_US
dc.identifier.endpage21en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorwosidErtek, Sibel / V-1593-2018
dc.authorwosidCesur, Mustafa / AAK-8083-2020
dc.authorscopusid6701335317
dc.authorscopusid36863887000
dc.authorscopusid15135521900
dc.authorscopusid23049519600
dc.authorscopusid6603696319
dc.authorscopusid6602380465
dc.authorscopusid7004246586
dc.identifier.wosqualityQ4
dc.identifier.wosWOS:000286512500011en_US
dc.identifier.scopus2-s2.0-79251516414en_US
dc.identifier.pmid20584061en_US


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