Advanced Search

Show simple item record

dc.contributor.authorGökçe, Mehmet İlker
dc.contributor.authorHamidi, Nurullah
dc.contributor.authorSüer, Evren
dc.contributor.authorTangal, Semih
dc.contributor.authorHüseynov, Adil
dc.contributor.authorİbiş, Arif
dc.date.accessioned2022-03-10T19:30:16Z
dc.date.available2022-03-10T19:30:16Z
dc.date.issued2015
dc.identifier.citationGokce, M. I., Hamidi, N., Suer, E., Tangal, S., Huseynov, A., & Ibiş, A. (2015). Evaluation of neutrophil-to-lymphocyte ratio prior to prostate biopsy to predict biopsy histology: Results of 1836 patients. Canadian Urological Association Journal, 9(11-12), E761-E765. https://doi.org/10.5489/cuaj.3091
dc.identifier.issn1911-6470
dc.identifier.issn1920-1214
dc.identifier.urihttps://doi.org/10.5489/cuaj.3091
dc.identifier.urihttps://hdl.handle.net/20.500.14065/2906
dc.description.abstractIntroduction: We evaluate the role of NLR prior to prostate biopsy to predict biopsy histology and Gleason score in patients with prostate cancer. Methods: In this retrospective study, we evaluated data of patients underwent prostate biopsy between May 2005 and March 2015. We collected the following data: age, prostate-specific antigen (PSA), biopsy histology, Gleason score (GS) in prostate cancer patients, neutrophil counts, and lymphocyte counts. Patients were grouped as benign prostatic hyperplasia (BPH), prostate cancer, and prostatitis. The Chi square test was used to compare categorical variables and analysis of variance (ANOVA) was applied for continuous variables. Results: Data of 1836 patients were investigated. The mean age, total PSA and neutrophil-lymphocyte ratio (NLR) of the population were 66.8 +/- 8.17 years, 9.38 +/- 4.7 ng/dL, and 3.11 +/- 1.71, respectively. Patients were divided as follows: 625 in the group with BPH history, 600 in the prostatitis group, and 611 in the prostate cancer histology group. The mean NLR of the prostatitis group was higher compared to the prostate cancer and BPH groups (p = 0.0001). The mean NLR of the prostate cancer group was significantly higher compared to the BPH group (p = 0.002). The GS 8-10 group had a significantly higher mean NLR compared to GS 5-6 (3.64 vs. 2.54, p = 0.0001) and GS 7 (3.64 vs. 2.58, p = 0.0001) patients. Conclusions: NLR was found to differ with regard to histology of prostate biopsy and higher GS was associated with higher NLR in patients with prostate cancer. However prostatitis prevents the use of NLR in predicting prostate cancer before a prostate biopsy. Also, the retrospective nature and lack of multivariate analysis in this study somewhat limits the relevance of these results.en_US
dc.language.isoengen_US
dc.publisherCanadian Urological Associationen_US
dc.relation.ispartofCuaj-Canadian Urological Association Journalen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Reactive proteinen_US
dc.subjectCanceren_US
dc.subjectInflammationen_US
dc.subjectMenen_US
dc.subjectAssociationen_US
dc.subjectBiomarkeren_US
dc.subjectSurvivalen_US
dc.subjectAntigenen_US
dc.titleEvaluation of neutrophil-to-lymphocyte ratio prior to prostate biopsy to predict biopsy histology: results of 1836 patientsen_US
dc.typearticleen_US
dc.authoridTangal, Semih / 0000-0003-1394-2454
dc.departmentTıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ürolojien_US
dc.institutionauthorTangal, Semih
dc.identifier.doi10.5489/cuaj.3091
dc.identifier.volume9en_US
dc.identifier.issue11-12en_US
dc.identifier.startpageE761en_US
dc.identifier.endpageE765en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid25638427100
dc.authorscopusid55371148900
dc.authorscopusid13805770800
dc.authorscopusid21740201100
dc.authorscopusid56950850300
dc.authorscopusid56950891000
dc.identifier.wosqualityQ3
dc.identifier.wosWOS:000373177500001en_US
dc.identifier.scopus2-s2.0-84946569747en_US
dc.identifier.pmid26600880en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record