Effects of crt monitor-emitted radiation in rat tissues: preventive effect of vitamin C

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2012Author
Kılıçoğlu, Sibel SerinTabak, Selçuk
Avcı, Aslıhan
Kılıçoğlu, Bülent
Devrim, Erdinç
Ergüder, Berrin İmge
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Kilicoglu, S.S.; Tabak, S.; Avcı, A.; Kilicoglu, B.; Devrim, E. & Erguder, B.I.(2012) Effects of crt monitor-emitted radiation in rat tissues: Preventive effect of Vitamin C. (2013). Nobel Medicus, 8(3), 81-86. https://www.scopus.com/record/display.uri?eid=2-s2.0-84872965116&origin=resultslist&sort=plf-f&src=s&st1=Effects+of+crt+monitor-emitted+radiation+in+rat+tissues%3a+Preventive+effect+of+Vitamin+C&sid=80675301c97f60dcf59e7e817fb8cb55&sot=b&sdt=b&sl=102&s=TITLE-ABS-KEY%28Effects+of+crt+monitor-emitted+radiation+in+rat+tissues%3a+Preventive+effect+of+Vitamin+C%29&relpos=0&citeCnt=0&searchTerm=&featureToggles=FEATURE_NEW_DOC_DETAILS_EXPORT:1Abstract
Objective: To investigate the effects of CRT (cathode ray tube)-monitor-emitted radiation on the oxidant/antioxidant status in kidney, liver, heart, brain tissues of rats and to observe the histo pathological findings of these tissues, and to examine any protective role of vitamin C supplementation. Material and Method: The study carried out on 40 Wistar albino adult female rats. There were 10 animals in each four group (control, vitamin C, computer; and computer plus vitamin C). The computer and computer plus vitamin C groups were exposed to computer monitors while the other groups were not. Vitamin C was administered 250 mg/kg/day orally. In the kidney, liver, heart, and brain tissues, malondialdehyde (MDA) levels and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were measured spectrophotometrically. In addition, histopathological examination is carried out. Results: In the kidney tissues, MDA levels significantly increased in the computer group compared with the computer plus vitamin C group and the control group (p<0.05). Histomorphologic changes were observed in the kidney and liver tissues of the computer group while there were no alterations in other tissues. Conclusion: The results of this study suggest that CRT-monitor-emitted radiation leads to oxidative stress and cellular changes in kidney and liver tissues and the antioxidant supplementation like vitamin C could prevent these possible oxidative effects.